DAY 1 IS SOLD OUT

08:30

Registration and coffee

9:30-11:00

Chairs: James Spicer, Sophia Karagiannis

09:30

Welcome and introductions

King’s College London, Cancer Research UK

EXPERIMENTAL CANCER MEDICINE CENTRES IMMUNOTHERAPY WORKSHOP “EMERGING CANCER IMMUNOLOGY FOR NEW THERAPIES”

09:45

Introduction

ECMC Chair

SESSION 1: NEXT GENERATION THERAPEUTICS | 10:00-13:00

10:00
The future of immune cell therapies

Dr Sophie Papa

The future of immune cell therapies

King’s College London

10:30
IgE Antibodies for Cancer Therapy

Prof Sophia Karagiannis

IgE Antibodies for Cancer Therapy

King's College London

11:00

Coffee and networking

11:30- 13:00

Chairs: Daniel Palmer, Juanita Lopez

11:30
Viral vectors for gene therapy of cancer

Prof Farzin Farzaneh

Viral vectors for gene therapy of cancer

King's College London

12:00
New T-cell targets

Prof Sergio Quezada

New T-cell targets

University College London

12:30
Key determinants of Antibody immunotherapy

Prof Mark Cragg

Key determinants of Antibody immunotherapy

University of Southampton

13:00

Lunch and poster presentation

14:00- 15:30

Chairs: Bristi Basu, Stefan Symeonides

SESSION 2: EMERGING THERAPEUTIC TARGETS 14:00-18:00

14:00
Myeloid derived suppression

Dr Carmela De Santo

Myeloid derived suppression

University of Birmingham

14:30
Macrophages: Bad Actors in Cancer

Prof Jeffrey Pollard

Macrophages: Bad Actors in Cancer

University of Edinburgh

15:00
γδ T cells in cancer therapy

Prof Ben Wilcox

γδ T cells in cancer therapy

University of Birmingham

15:30

Coffee and networking

16:00-18:00

Chairs: Deb Joseph-Pietras, Fiona Thomson

16:00
Metabolic underpinnings of trained NK cell function

Prof Christoph Hess

Metabolic underpinnings of trained NK cell function

University of Basel, Switzerland

16:30
The heterogeneity of Tregs in cancer – opportunity or liability?

Dr Shahram Kordasti

The heterogeneity of Tregs in cancer – opportunity or liability?

King’s College London

17:00
Learning in vivo: how data science and cytomics are connecting cell biology and cancer

Dr Jonathan Irish

Learning in vivo: how data science and cytomics are connecting cell biology and cancer

Vanderbilt University, US

18:00

Reception and poster presentation

DAY 2 IS SOLD OUT

08:00

Registration and coffee

08:30-9:00

Chairs: Peter Parker

08:30
Julie Brahmer, Keynote speaker

Prof Julie Brahmer

Julie Brahmer, Keynote speaker

Johns Hopkins, US

SESSION 3: BIG DATA AND PRECISION MEDICINE - GENERATION I | 09:00-13:05

09:00-11:05

Chairs: Anita Grigoriadis, Ben Willcox

9:00
Adaptive mutability of cancers in response to targeted therapies

Prof Alberto Bardelli

Adaptive mutability of cancers in response to targeted therapies

University of Turin, Italy

09:25
Clonal evolution in cancer and clinical utility

Prof Joop Jansen

Clonal evolution in cancer and clinical utility

Radboudumc, Netherlands

9:50
Genomics and patient stratification

Dr Andrew D Beggs

Genomics and patient stratification

University of Birmingham

10:15
Neoantigen prediction in the clinic

Dr Samra Turajlic

Neoantigen prediction in the clinic

The Francis Crick Institute

10:40
Complement and cancer related inflammation

Dr. Dimitrios Mastellos

Complement and cancer related inflammation

National Centre for Scientific Research, Greece

11:05

Coffee and networking

11:20-13:05

Chairs: Claire Shannon, Shahram Kordasti

11:20
Lymphoid stress surveillance: a window on troubling immunological ignorance

Prof Adrian Hayday

Lymphoid stress surveillance: a window on troubling immunological ignorance

King’s College London & University College London

11:50
Building prognostic and predictive models for human cancer using big data

Dr Ash Alizadeh

Building prognostic and predictive models for human cancer using big data

Stanford University, US

12:15
The clinical immunome in solid cancers

Dr Jerome Galon

The clinical immunome in solid cancers

INSERM, France

12:40
The clinical immunome in haematological malignancies

Dr Nichola Cooper

The clinical immunome in haematological malignancies

Imperial College London

13:05 - 14:00

Lunch and poster presentation

Session 4: Big Data and Precision Medicine – Generation II | 14:00-18:00

14:00-15:30

Chairs: James Arnold, Sheeba Irshad

14:00
Microbiome and cancer

Dr Jennifer Wargo

Microbiome and cancer

MD Anderson, US

14:25
Which microbiome signature(s) and how?

Dr Saeed Shoaie

Which microbiome signature(s) and how?

Kings’ College London

14:50
Epigenome and T-cell fate

Dr Ben Afzali

Epigenome and T-cell fate

National Institute of Health, US

15:15

Selected Abstract: CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype

Juliana Candido- Queen Mary University of London

15:30

Coffee and networking

16:00-18:00

Chairs: Tony Ng, Adrian Hayday

16:00
Intracellular innate immunity and response to immunotherapy

Dr Eileen Parkes

Intracellular innate immunity and response to immunotherapy

Queen’s University Belfast

16:25
Molecular imaging of the tumour metropolis

Dr Josephine Bunch

Molecular imaging of the tumour metropolis

Imperial College London

16:50

Selected Abstract: The antimicrobial peptide LL-37 generates dendritic cells optimised for immunotherapy

Emily Findlay- University of Edinburgh

17:05

Selected Abstract: Profiling the normal colonic mucosa in synchronous colorectal cancer by Imaging Mass Cytometry

Michele Bortolomeazzi- King's College London

17:25
Debate: Allogeneic CAR-T products will largely replace autologous cells within 5 years; Arguments for and against.

Prof Paul Moss

Debate: Allogeneic CAR-T products will largely replace autologous cells within 5 years; Arguments for and against.

Paul Moss (University of Birmingham) & Farzin Farzaneh (King’s College London)

18:00

Reception and poster presentation

19:30

Speakers' dinner reception

DAY 3 IS SOLD OUT

08:00

Registration and coffee

SESSION 5: TRANSLATING BIG DATA TO ROUTINE DIAGNOSTIC TESTS – IMPLEMENTATION | 08:50-13:00

8:50- 11:00

Chairs: Trevor Graham (Bart’s), Johnathan Irish

08:50
Working with big data; challenges and rewards

Prof Ton Coolen

Working with big data; challenges and rewards

King’s College London

09:20
Big data in time and space

Prof Francesca Ciccarelli

Big data in time and space

The Francis Crick Institute

09:45
Combining clinical and laboratory data to identify patient populations

Dr Duncan Murray

Combining clinical and laboratory data to identify patient populations

University of Birmingham

10:05
Prediction models based on big data

Prof Benjamin Vincent

Prediction models based on big data

Lineberger Cancer Centre, UNC, Chapel Hill

10:30

Debate: Do I still need my microscope?

Arjan Van de Loosdrecht (Amsterdam University, Netherlands) & Robin Ireland (King’s College Hospital)

11:00

Coffee and networking

11:30-13:00

Chairs: Francesco Dazzi, Mieke van Hemelrijck

11:30

Selected Abstract: Artificial intelligence improves flow cytometry diagnostics in myelodysplastic syndromes

Carolien Duetz- Amsterdam University Medical Center

11:45

Selected Abstract: Single-cell systems neuroimmunology reveals immunosuppressive correlates with ventricular stem cell niche contact in human glioblastoma

Todd Bartkowiak- Vanderbilt University

12:00

Selected Abstract: Contrasting drivers of response to immunotherapy across solid tumour types: results from analysis of >1000 cases

Kevin Litchfield- The Francis Crick Institute

12:20
Clinical implementation of stratified immuno-oncology

Prof Sean Whittaker

Clinical implementation of stratified immuno-oncology

King’s College London

12:40

Closing remarks

PARALLEL WORKSHOPS | 14:00-18:00

14:00 - 18:00

Option A: Genomics

Leads: Paul Lavender (King’s College London) & Andrew Beggs (University of Birmingham)

14:00 - 18:00

Option B: Cytometry and immunomics (Sold Out)

Leads: Susanne Heck (Guy’s & St. Thomas Trust) & Graham Taylor (University of Birmingham)

14:00 - 18:00

Option C: Clinical data science: integrating immunomics, genomics and clinical data (Sold Out).

Leads: Shahram Kordasti (King’s College London) & Jonathan Irish (Vanderbilt University)

For any additional information, please get in touch